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PowerPuff girls meet PinkiePuff girls, a 3 girls, similiar to them, created by unknown scientist. But RowdyRuff boys meet alter ego´s of this girls: RadioRuff boys

Voices:

Cathy Cavadini as Blossom

Hynden Walch as Bubbles

E.G Daily as Buttercup

Susanne Blakeslee as Barbara

Grey DeLisle as Beatrix

Jane Carr as Berenice

Rob Paulsen as Brick/Boomer

Greg Cipes as Butch

Tom Kenny as narrator/Balthasar

Carlos Alazraqui as Barnabas

Daran Norris as Barry

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